PreviaTest is a non-invasive prenatal test (NIPT) for pregnant women. The PreviaTest estimates the risk of a fetus having Down syndrome (Trisomy 21), Edwards’ syndrome (Trisomy 18) and Patau’s syndrome (Trisomy 13) with an accuracy of over 99%. This advanced screening test is carried out on a small maternal blood sample. Pregnant women can expect test results from their healthcare provider within 5-7 days from sample receipt. With EluthiaCare pregnant women and physicans get access to addional service an counselling at no additional costs.
What does PreviaTest screen for?
PreviaTest detects the fetus’ risk of being affected by Down syndrome (trisomy 21), Edwards syndrome (trisomy 18) or Patau syndrome (trisomy 13). A trisomy occurs when there are three instances of a particular chromosome instead of the normal two. Edwards syndrome and Patau syndrome occur significantly less frequent than Down syndrome. However, both syndromes are very serious and usually lead to the baby’s death during its first couple of months alive. Optionally, PreviaTest can determine the fetus’ gender with an accuracy of over 99%. In some rare cases PreviaTest can’t determine the gender because of insufficient information. That however does not impact the accuracy of the trisomy screening.
What are the advantages of PreviaTest?
Safe: Non-invasive and therefore without risk of causing a miscarriage.
Fast: Results are usually available within 5-7 days.
Precise: Both the detection rate for trisomies as well as sex determination are above 99%.
Simple: PreviaTest only requires a blood sample of the pregnant woman.
High Quality: PreviaTest is certified by the CE.
How does PreviaTest work?
During pregnancy placental DNA can be found circulating in the mother’s blood. Therefore, the blood contains both fetal placental DNA as well as maternal, circulating, cell-free DNA. PreviaTest measures the percentage of this cell-free DNA and can therefore detect small deviations between cell-free maternal DNA and cell-free fetal DNA. This data is then used to detect a trisomy 21, 18 or 13.
How do I get the most complete prenatal screening?
Usually, pregnant women are examined in a first trimester screening. This includes a nuchal translucency screening via ultrasound as well as an analysis of biochemical markers. When detecting trisomies, this method is not as precise as an NIPT (85-90%). However, a first trimester screening is useful for recognizing maternal and fetal complications at an early stage. PreviaTest (IONA® technology) is the only NIPT capable of taking into account the risk calculation generated by a first trimester screening. Therefore, PreviaTest offers pregnant women a complete and sound prenatal screening.
PreviaTest can be carried out from the 11th week of pregnancy onwards. Women oftentimes choose PreviaTest in addition to the mandatory check-up via ultrasound. PreviaTest has a better detection rate for trisomies than the standard first trimester screening. Therefore, fewer women have to undergo an invasive follow-up procedure (amniocentesis) which can be painful and which carries with itself a small risk of causing a miscarriage.
Who is suitable for PreviaTest?
- Pregnant women from gestational week 11 onwards (10 weeks + 0 days)
- Singleton or twin pregnancies
- IVF, donor egg or surrogate pregnancies
Who is unsuitable for PreviaTest?
Unsuitable if the mother has:
- Undergone Stem Cell Therapy or Immunotherapy
- Organ transplants
How are PreviaTest results reported?
Low risk: An occurrence of trisomy 21, 18 or 13 is highly unlikely.
High risk: There is a heightened risk for trisomy 21, 18 or 13. Confirmation of the result via an invasive procedure (e.g. amniocentesis) is urgently advised.
No result: In rare cases, a sample does not contain enough fetal DNA to generate a result. In that case you will be asked to take a second blood sample.
Talk to your healthcare provider to find out if the PreviaTest is right for you.
Is it possible to determine the gender with PreviaTest?
Sex determination is optional. The accuracy is above 99%. In some rare cases PreviaTest can’t determine the gender because of insufficient information. That however does not impact the accuracy of the trisomy screening.
Where can I get PreviaTest?
IONA® is a registered trademark of Premaitha Health plc.
Premaitha Limited trading as Premaitha Health. Its registered office is at Rutherford House, Manchester Science Park, Manchester, M15 6SZ, UK.
PreviaTest® is a registerd trademark of Eluthia GmbH: Im Bosseldorn 30, 69126 Heidelberg, Germany.